Mastelli Plinest 1x2ml

What is Mastelli Plinest and what is the PN-HPT® technology?

Mastelli Plinest is a next-generation biorevitalisation preparation whose key strength is the patented PN-HPT® — Polynucleotides Highly Purified Technology. This is an advanced purification process for polynucleotides from a strictly selected natural source, ensuring:

• Exceptional purity and safety — elimination of potentially allergenic proteins, precise molecular fraction control,
• Consistent, reproducible active concentration (20 mg/ml) — guarantee of predictable clinical results,
• Outstanding biocompatibility — excellent skin tolerability,
• Multidirectional biological action — PN-HPT® polynucleotides simultaneously act as a substrate for cellular regeneration, hydrating agent and ECM rebuilding stimulator.

Mastelli Plinest vs Plinest Fast

Indications and treatment areas

• Skin biorevitalisation — deep cellular-level reconstruction and regeneration,
• Firmness and elasticity improvement,
• Fine wrinkle reduction,
• Photo-ageing and oxidative stress correction,
• Recovery after dermatological and aesthetic procedures,
• Preventive anti-ageing — slowing ageing processes.

Treatment areas: face · neck · décolletage · hands

Treatment protocol

• Initial series: 3–4 sessions every 2–3 weeks,
• Results: visible after the first session, lasting several months,
• Route: intradermal injections.

Composition and package contents

• Active substance: Polynucleotides PN-HPT® 20 mg/ml
• Contents: 1 × prefilled syringe 2 ml
• EAN: 8053303261373
• Manufacturer: Mastelli S.r.l., Via Armea 90, 18038 Sanremo, Italy

FAQ – questions and answers

What sets PN-HPT® technology apart from standard polynucleotides?

Most polynucleotide preparations (PDRN) differ in purification quality and molecular fraction standardisation. Mastelli's proprietary PN-HPT® (Highly Purified Technology) ensures an exceptionally high degree of source material purity and precise active concentration. Elimination of protein fractions minimises allergic reaction risk, while concentration reproducibility delivers predictable clinical results with every treatment.

How soon are results visible and how long do they last?

Results are visible after the very first session and intensify with subsequent treatments. The full result of the treatment series (3–4 sessions at 2–3 week intervals) lasts several months — the exact duration depends on patient age, skin condition and lifestyle.

How does Plinest differ from Plinest Fast?

Plinest (this product) is the classic PN-HPT® biorevitalisation formula for regeneration and anti-ageing. Plinest Fast is a variant with a faster-acting formula. Both versions are based on the same PN-HPT® technology and differ in kinetic profile and specific application.

Mastelli Plinest is intended exclusively for use by doctors and cosmetologists trained in aesthetic medicine holding qualifications to perform intradermal injections. By purchasing this product you confirm that you hold the required professional qualifications.

• What is Mastelli Plinest and what is PN-HPT® technology?
• Mastelli Plinest vs Plinest Fast
• Indications and treatment areas
• Treatment protocol
• Composition and package contents
• FAQ